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Hydrazide compounds as thyroid hormone receptor modulators and uses thereof
专利权人:
Herbert H. Samuels
发明人:
Herbert H. Samuels,Ruben Abagyan,Matthieu Schapira,Maxim Totrov,Bruce M. Raaka,Stephen R. Wilson,Li Fan,Zhiguo Zhou
申请号:
US12450922
公开号:
US08394811B2
申请日:
2008.04.18
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A method of identification of compounds that modulate thyroid hormone activity, and the use of such compounds and compositions thereof for such purposes are disclosed. The compounds may be selected from the group consisting of:The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of conditions that are causally related to aberrant thyroid hormone activity, such as hyperthyroidism and thyrotoxicosis.
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