Olaf Schneewind,Alice Cheng,Dominique M. Missiakas,Hwan Keun Kim
申请号:
US14968023
公开号:
US09907850B2
申请日:
2015.12.14
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant or an antibody directed thereto.