MEHTA, Kamal Surendrakumar,KUMAR, Dinesh,SRIVASTAVA, Saurabh,PAUL, Basudev
申请号:
EP17857958
公开号:
EP3523288A4
申请日:
2017.10.06
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention relates to a solid oral pharmaceutical dosage form suitable for making a suspension comprising acid labile benzimidazole compounds and process for preparing the same. The prior art discloses various technical challenges associated with the granules for reconstitution into suspension like agglomeration of particles, viscosity and gelling time. The solid oral pharmaceutical dosage form of the present invention forms a homogeneous suspension upon admixing with an aqueous medium and exhibits desired technical attributes like viscosity, drug release, gelling time, dissolution and reduced adherence to nasogastric and gastric tubes.