Axl receptor tyrosine kinase aptamer inhibitor for use in therapy

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专利权人:

Vittorio De Franciscis

发明人:

Vittorio De Franciscis,Laura Cerchia

申请号：

US13876103

公开号：

US08741870B2

申请日:

2011.10.10

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The present invention concerns a nucleotide aptamer having the sequence: 5′-AUGAUCAAUCGCCUCAAUUCGACAGGAGGCUCAC-3′(SEQ ID NO: 1) for use in the treatment and/or prevention and/or diagnosis of an Axl receptor tyrosine kinase induced disorder and a pharmaceutical composition comprising the same. The invention also relates to a method for the diagnosis of an Axl receptor tyrosine kinase induced disorder in a patient from which a sample is obtained and related diagnostic kit.

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中国工程科技知识中心

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http://www.ckcest.cn/home/