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1, 3-DIHYDROIMIDAZOLE- 2 -THIONE DERIVATIVES AS INHIBITORS OF DOPAMINE-BETA-HYDROXYLASE
专利权人:
BIAL-PORTELA & CA. S.A.
发明人:
SOARES DA SILVA, PATRICIO MANUEL VIEIRA ARAUJO,LEARMONTH, DAVID ALEXANDER,BELIAEV, ALEXANDER
申请号:
HK10109325.5
公开号:
HK1142898B
申请日:
2010.09.29
申请国别(地区):
HK
年份:
2013
代理人:
摘要:
Compounds of formula I and a method for their preparation are described: where R1, R2 and R3 are the same or different and signify hydrogens, halogens, alkyl, nitro, amino, alkylcarbonylamino, alkylamino or dialkylamino group R4 signifies -alkyl-aryl or -alkyl-heteroaryl X signifies CH2, oxygen atom or sulphur atom n is 2 or 3 including the individual (R)- and (S)-enantiomers or mixtures of enantiomers thereof and including pharmaceutically acceptable salts and esters thereof. The compounds have potentially valuable pharmaceutical properties for the treatment of cardiovascular disorders such as hypertension and chronic heart failure.
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中国工程科技知识中心
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http://www.ckcest.cn/home/
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