Pain is treated or prevented with what, the compound including acute and chronic pain (for example, nociceptive pain, neuropathic pain, headache, migraine), be expressed as general formula I: wherein: Xu Line represents singly-bound or double bond； And R5 and R5 ' is independently-H ,-OH or-OR6, and wherein R6 is the C1-C4 alkyl of straight chain or branch； X is-CH2O-； Z is-CH2CH2O-CH (CH3) CH2O- or-CH2CH (CH3) O-； M is 1； And n is the integer of 1-5. The compound of the present invention can also be reduced inflammation with effective what and can be used alone or be combined with other antalgesics.用於治療或預防疼痛，包括急性和慢性疼痛（例如，傷害性疼痛、神經性疼痛、頭痛、偏頭痛）的化合物，其表示爲通式I：其中：虛綫代表單鍵或雙鍵；並且R5和R5′獨立地是-H、-OH或-OR6，其中R6是直鏈的或支鏈的C1-C4烷基；X是-CH2O-；Z是-CH2CH2O-CH(CH3)CH2O-或-CH2CH(CH3)O-；m是1；並且n是1-5的整數。本發明的化合物也可以有效用於降低炎症並且可以單獨使用或與其他鎮痛藥聯用。
