The present invention relates to a microemulsion comprising: 1-98 wt% of at least one polar lipid selected from polyglycerol fatty acid esters； 1-98 wt% of at least one emollient, not being a polyglycerolfatty acid ester； 0.1-3 wt% of at least one polar solvent； and 0-10 wt% of a surfactant, not being a polyglycerol fatty acid ester. The present invention further relates to said microemulsion for use as a medicament, and for use in the treatment and prevention of dry mucosa or prevention of airborne particles reaching topical mucosal membranes of a mammal. The present invention also relates to a liquid composition comprising said microemulsion, and an applicator device comprising said microemulsion.
