Xolani Mthembu;Louis Ackerman;Vinesh Jaichand Maharaj;Gerda Fouche;Marina Van Der Merwe
发明人:
Gerda Fouche,Vinesh Jaichand Maharaj,Xolani Mthembu,Louis Ackerman,Marina Van Der Merwe
申请号：
US12734373
公开号：
US09061023B2
申请日:
2008.04.08
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention provides the use of an extract of a plant of the genus Elephantorrhiza and at least one compound selected from quercitin-3′-O-glucoside, trans-3-O-galloyl-3,3′,5,5′,7-pentahydroxyflavan, taxifolin-3′-O-glucoside, catechin and epicatechin in the preparation of a medicament for the treatment of benign prostatic hyperplasia (BPH). The mode of action is by a route selected from blocking the conversion of testosterone to dihydrotestosterone by inhibiting the 5α-reductase enzyme or by reducing oxidative stress or both.
