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疎水性基で官能基化された分岐鎖ポリアミノ酸、及びその応用、特に治療への応用
专利权人:
フラメル・テクノロジー
发明人:
スーラ レミ,プーリケン ゴーティエ,チャン ユ-ピン
申请号:
JP2007523128
公开号:
JP4871867B2
申请日:
2005.07.19
申请国别(地区):
JP
年份:
2012
代理人:
摘要:
The invention concerns novel materials based on biodegradable branched polyaminoacids particularly useful for transporting active principle(s). The invention also concerns novel pharmaceutical, cosmetic, dietetic or phytosanitary compositions based on polyaminoacids. The invention aims at providing a novel polymeric material, capable of being used for transporting active principle(s) and enabling all the required relevant specifications to be optimally satisfied: biocompatibility, biodegradability, easy ability to be combined with a large number of active principles or to solubilize same, and to release the active principles in vivo. This is achieved by the present invention which firstly concerns branched polyaminoacids comprising aspartic acid units and or glutamic acid units, and which bear hydrophobic groups including 8 to 30 carbon atoms. The branched polyaminoacids are amphiphilic and are capable of being easily and economically transformed into particles for transporting active principles, the particles being themselves capable of forming stable aqueous colloidal suspensions.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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