To provide a medical observation device, information processing method, program, and video microscope device.A medical observation device including: a selection unit configured to select one reference camera from two or more cameras； a motion detection unit configured to detect a motion of the reference camera； a first correction information acquisition unit configured to acquire first correction information that lessens the motion of the reference camera； and a second correction information acquisition unit configured to acquire second correction information that lessens a motion of a camera other than the reference camera included in the two or more cameras using a method different from a method of the first correction information acquisition unit.
