KEHOE, John,LEE, Jennifer,ORT, Tatiana,PICHA, Kristen,RYAN, Mary,WHEELER, John
申请号：
USUS2011/053250
公开号：
WO2012/047583A3
申请日:
2011.09.26
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The disclosure provides isolated monoclonal antibodies or fragments thereof that bind human collagen II. Specifically, the disclosure provides antibodies each comprising a heavy chain variable region and a light chain variable region sequence with specified CDR region sequences. Further provided are polynucleotide sequences encoding human collagen II antibodies or fragments thereof. The methods of making and using the antibodies are also disclosed.La présente invention concerne des anticorps dirigés contre le collagène humain de type II, des polypeptides et des polynucléotides codant pour les anticorps anti-collagène humain de type II ou leurs fragments, et des procédés permettant de fabriquer et d'utiliser ce qui précède.
