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ВВЕДЕНИЕ ЭРИТОРАНА ИЛИ ЕГО ФАРМАЦЕВТИЧЕСКИ ПРИЕМЛЕМЫХ СОЛЕЙ ДЛЯ ЛЕЧЕНИЯ ОРТОМИКСОВИРУСНЫХ ИНФЕКЦИЙ
专利权人:
ЮНИВЕРСИТИ ОФ МЭРИЛЕНД; БАЛТИМОР (US)
发明人:
ВОГЕЛЬ Стефани (US),ШИРИ Кери Энн (US)
申请号:
RU2014138880
公开号:
RU2014138880A
申请日:
2013.03.04
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. A method of treating a patient infected with influenza virus comprising administering to an infected patient a therapeutically effective amount eritorana or a pharmaceutically acceptable soli.2. A method according to Claim. 1 further comprising administering to the infected patient a therapeutically effective amount of an antiviral soedineniya.3. The method of claim. 1, characterized in that the infected patient is administered a therapeutically effective amount eritorana or a pharmaceutically acceptable salt thereof after a positive test result for the presence grippa.4 infection. A method according to claim. 3, characterized in that for the infected patient test for Influenza infection was carried out using the polymerase chain reaction (PCR), direct tests on antigen detection by reverse transcription PCR (RT-PCR, rt-PCR), virus isolation in cell culture or kombinatsiy.5. A method according to Claim. 1 further comprising providing a reducing mRNA levels induced by influenza virus in infected patsienta.6 cytokines. The method of claim. 5, further comprising providing a reducing mRNA levels of influenza virus-induced cytokine in an infected patient, wherein said cytokines include tumor necrosis factor α (TNF-α), IL-1β, IL-6, COX-2, IL 12 p40, KS, IL-10, IL-5, tumor growth factor β (FRO-β) or kombinatsii.7. A method according to Claim. 1 further comprising providing a reducing mRNA levels induced by interferon beta influenza virus or interferon gamma in infected patsienta.8. The method of claim. 1, characterized in that the infected patient is administered a therapeutically effective amount, or a pharmaceutically eritorana PRIE1. Способ лечения пациента, инфицированного вирусом гриппа, включающий введение инфицированному пациенту терапевтически эффективного количества эриторана или его фармацевтически приемлемой соли.2. Способ по п. 1, дополнительно включающий введение инфицированному пациенту терапевтически эффективного количества противовирусного соединения.3. С
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