ABEYWARDANE, ASITHA,BURKE, MICHAEL J.,KIRRANE, THOMAS MARTIN, JR.,NETHERTON, MATTHEW RUSSELL,PADYANA, ANIL KUMAR,SMITH KEENAN, LANA LOUISE,TAKAHASHI, HIDENORI,TURNER, MICHAEL ROBERT,ZHANG, QIANG,ZHANG
申请号:
CA2835617
公开号:
CA2835617A1
申请日:
2012.03.13
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention relates to compounds of formula (I): wherein R1 to R3, A, X and n are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorder. The present invention also relates to pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.