recombinant polypeptide, nucleic acid sequence, host cell, bionanoparticle, methods for producing a bionanoparticle and for treating or preventing dengue virus, and vaccine.
INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY
发明人:
NAVIN KHANNA,VISWANATHAN RAMASAMY
申请号:
BR112017004008
公开号:
BR112017004008A2
申请日:
2015.08.21
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
The invention provides a recombinant polypeptide comprising the ediii domain of each of the denv-1, denv-2, denv-3 and denv-4 dengue virus serotypes linked to the hbsag n-terminus.a invenção provê um polipeptídeo recombinante que compreende o domínio ediii de cada um dos sorotipos do vírus da dengue denv-1, denv-2, denv-3 e denv-4 ligados ao n-terminal de hbsag.