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human growth hormone receptor antagonist antibodies and methods of use
专利权人:
RINAT NEUROSCIENCE CORP.
发明人:
CHIA-YANG LIN,EDWARD DERRICK PASCUA,JAVIER FERNANDO CHAPARRO RIGGERS,SARA IVA SIEBEL
申请号:
BR112014014824
公开号:
BR112014014824A2
申请日:
2012.12.10
申请国别(地区):
BR
年份:
2019
代理人:
摘要:
Summary "Human Growth Hormone Receptor Antagonist Antibodies and Methods of Using Them" The present invention provides growth hormone receptor (ghr) binding antagonists. The invention further relates to therapeutic methods for using such antibodies to reduce levels of igf-1 and / or for the treatment and / or prevention of diseases associated with excessive igf-1, including treatment of acromegaly, gigantism, cancer, diabetic nephropathy, arthritis, and pulmonary inflammation.resumo “anticorpos antagonistas do receptor do hormônio de crescimento humano e métodos de uso dos mesmos" a presente invenção provê anticorpos antagonizantes que ligam ao receptor do hormônio de crescimento (ghr). a invenção ainda relaciona-se a métodos terapêuticos para uso desses anticorpos para reduzir níveis de igf-1 e/ou para o tratamento e/ou prevenção de doenças associadas com igf-1 excessivo, incluindo tratamento de acromegalia, gigantismo, câncer, nefropatia diabética, artrite, e inflamação pulmonar.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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