KORPHARM CO., LTD.;KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION;KOREA INSTITUTE OF RADIOLOGICAL &； MEDICAL SCIENCES
发明人:
Gil Hong Park,Geu Rim Son,Seong Su Hong,Chun Whan Choi,Yun Hyeok Choi,Woo Jung Kim,Han Kyeom Kim,Jae Woo Kang,Eun Jung Lee,Serk In Park,Kee Ho Lee,Min Ji Choi
申请号：
US16338354
公开号：
US20200129450A1
申请日:
2017.09.28
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to a composition comprising osmundacetone or a pharmaceutically acceptable salt thereof for preventing or treating bone diseases. More specifically, the present invention relates to: a composition comprising osmundacetone, a pharmaceutically acceptable salt thereof, or an Osmunda japonica extract as an effective ingredient, for preventing or treating osteoporosis, rheumatoid arthritis, arthralgia, Paget disease, bone metastatic cancer, or fracture； a food composition for improvement； a use of a salt； and a treatment method. The composition according to the present invention shows a strong inhibitory activity against proliferation and differentiation of osteoclast which causes bone loss, and activation of differentiation of osteoblast, and thus can be usefully utilized in developing medicines for safe and effective treatment of bone diseases or functional foods for improving symptoms of bone diseases
