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SUBSTITUTED PYRAZOLOPYRIMIDINONE COMPOUNDS AS PDE2 INHIBITORS
专利权人:
LLC;DART NEUROSCIENCE
发明人:
Laurent Gomez,William Francois Vernier
申请号:
US16473864
公开号:
US20200148685A1
申请日:
2017.12.22
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A chemical entity of Formula (I), wherein V, W, Y, and Z, have any of the values described herein, and compositions comprising such chemical entities, methods of making them; and their use in a wide range of methods, including metabolic and reaction kinetic studies; detection and imaging techniques, radioactive treatments; modulating and treating disorders mediated by PDE2 activity; treating neurological disorders, CNS disorders, dementia, cognitive disorders, neurodegenerative diseases, and trauma-dependent losses of function, enhancing the efficiency of cognitive and motor training, including in stroke or TBI rehabilitation; and treating peripheral disorders, including hematological, cardiovascular, gastroenterological, dermatoiogical, inflammatory, and pain disorders.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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