PROBLEM TO BE SOLVED: To provide a novel use of a peptide obtained from sake cake as a raw material.SOLUTION: According to the present invention, a lipid metabolism-improving agent comprises: (a) a peptide mixture produced by allowing a neutral protease and an acidic protease to act on sake cake (b) a peptide mixture produced by allowing a heat-resistant neutral protease derived from Bacillus bacterium to act on sake cake or (c) at least one peptide selected from the group consisting of Arg-Leu, Val-Gln, Ile-Tyr, Phe-Trp, Glu-Cys-Gly, Ile-Asn, Tyr-Pro, Leu-Asn, Gly-Ile, Pro-Arg, Pro-Trp, Tyr-Gly, Ile-Trp, Pro-Tyr, and Ile-Lys-Pro-Pro.SELECTED DRAWING: Figure 4COPYRIGHT: (C)2017,JPO&INPIT【課題】 酒粕を原料として得られるペプチドの新たな用途を提供する。【解決手段】 (a)酒粕に中性プロテアーゼ及び酸性プロテアーゼを作用させることにより生成するペプチド混合物、(b)酒粕にバチルス属細菌由来の耐熱性中性プロテアーゼを作用させることにより生成するペプチド混合物、又は(c)Arg-Leu、Val-Gln、Ile-Tyr、Phe-Trp、Glu-Cys-Gly、Ile-Asn、Tyr-Pro、Leu-Asn、Gly-Ile、Pro-Arg、Pro-Trp、Tyr-Gly、Ile-Trp、Pro-Tyr、及びIle-Lys-Pro-Proからなる群より選ばれる少なくとも1種のペプチドを含有する脂質代謝改善剤。【選択図】図4
