PROBLEM TO BE SOLVED: To provide probiotic compositions suitable for reducing the morbidity and duration of human disease, in particular, methods and compositions suitable for preventing disease in young children, especially, respiratory disease.SOLUTION: The invention provides cultures of Lactobacillus acidophilus and also cultures additionally combined with Bifidobacterium lactis, as well as a method for orally administering the cultures to a child at risk of suffering from respiratory disease provided that the risk of suffering from respiratory disease is decreased. As one of the methods of implementation, a method of preventing respiratory disease in children by supplying a supplement to which the cultures are added is provided.SELECTED DRAWING: Figure 1【課題】人の疾病の罹患率及び持続期間を減少するために適したプロバイオティック組成物、特に低年齢小児の疾患、とりわけ呼吸器疾患を予防するために適した方法及び組成物の提供。【解決手段】ラクトバチルス・アシドフィルスの培養物、更にビフィドバクテリウム・ラクティスを追加的に組み合わた培養物を提供し、呼吸器疾患に罹患する危険性のある小児を提供し、及び呼吸器疾患に罹患する危険性が減少する条件下、その小児に前記培養物を口から投与する方法。実施方法の一つとして前記培養物を栄養補助食品に添加して供給する、小児における呼吸器疾患の予防を行う方法。【選択図】図1