PROBLEM TO BE SOLVED: To provide a method for accurately predicting the therapeutic effectiveness of a chemotherapy in implementing the chemotherapy including a 5-fluorouracil anti-tumor agent in a cancer patient.SOLUTION: The expression level of at least one miRNA selected from miR-17, miR-17*, miR-20a, miR-20a*, miR-20b, miR-92a, miR-106a, miR-126*, miR-142-3p, miR-223, miR-630 and let-7a* contained in a biological sample collected from the patient is employed as a measure in the method for predicting the therapeutic effectiveness of the chemotherapy including the 5-fluorouracil anti-tumor agent in the cancer patient.COPYRIGHT: (C)2012,JPO&INPIT【課題】癌患者における、5-フルオロウラシル系抗腫瘍剤を含む化学療法の施行に当たり、その治療効果を精度良く予測できる方法の提供。【解決手段】患者から採取した生体試料に含まれるmiR-17、miR-17*、miR-20a、miR-20a*、miR-20b、miR-92a、miR-106a、miR-126*、miR-142-3p、miR-223、miR-630及びlet-7a*から選ばれる1以上のmiRNAの発現量を指標とした、癌患者における5-フルオロウラシル系抗腫瘍剤を含む化学療法に対する治療効果を予測する方法。【選択図】なし
