Chunhua Jin,Xiaoyu Liu,Zhenliang Chen,Xiaohe Zheng,Shoufeng Ming
申请号:
US13057737
公开号:
US08822519B2
申请日:
2009.08.07
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides a novel compound of formula I, which has an agitation effect on the peroxisome proliferator-activated receptor subtype δ (PPARδ), to a pharmaceutical composition comprising the compound, to a process for preparation of the compound and to use of the compound in the manufacture of a medicament for treating or preventing a disease which could be treated or prevented by activating PPARδ thereof, said disease is one or more from the group comprising metabolic syndrome, obesity, dyslipidemia, pathoglycemia, insulin resistance, senile dementia and tumors. The present invention also relates to a new intermediate used in the preparation of the novel compound and a process for preparation of the intermediate.