Therapy regimen and methods to sensitize cancer cells treated with epigenetic therapy to PARP inhibitors in ovarian cancer

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专利权人:

THE JOHNS HOPKINS UNIVERSITY;UNIVERSITY OF MARYLAND, BALTIMORE

发明人:

Feyruz Rassool,Stephen Baylin,Carine Robert,Khadiza Chowdhury,Nidal Muvarak

申请号：

US15254716

公开号：

US10105382B2

申请日:

2016.09.01

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The presently disclosed subject matter provides methods to treat cancer cells using low doses of DNA demethylating agents and poly ADP ribose polymerase (PARP) inhibitors. Methods also are provided for sensitizing a cell to a PARP inhibitor.

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中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/