IDENTIFICATION OF PREDICTIVE BIOMARKERS ASSOCIATED WITH WNT PATHWAY INHIBITORS

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专利权人:

ONCOMED PHARMACEUTICALS; INC.

发明人:

KAPOUN, ANN M.,卡保恩 安,卡保恩 安,ZHANG, CHUN,张春,張春

申请号：

TW103141799

公开号：

TW201610168A

申请日:

2014.12.02

申请国别(地区):

TW

年份:

2016

代理人:

摘要：

The present invention provides biomarkers for identifying tumors likely to respond to treatment with Wnt pathway inhibitors. Also provided are methods for identifying tumors and/or patients that are likely to be responsive or non-responsive to treatment with a Wnt pathway inhibitor. Methods for treating a patient with cancer are provided, wherein the cancer is predicted to respond to a Wnt pathway inhibitor.本發明提供用於鑑別可能對Wnt途徑抑制劑之治療有反應的腫瘤之生物標記。本發明亦提供用於鑑別可能對Wnt途徑抑制劑之治療有反應或無反應的腫瘤及/或病患之方法。本發明提供用於治療癌症病患之方法,其中該癌症係經預測為對Wnt途徑抑制劑有反應。

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/