A physiological status monitoring device includes a monitoring module and a fixing module. The monitoring module includes a first housing configured to be arranged at a first side of a flexible object, a monitoring unit arranged in the first housing for monitoring a physiological status of a human body, a first processing unit electrically connected to the monitoring unit for controlling operations of the monitoring unit, and a first magnetic fixing unit connected to the first housing. The fixing module includes a second housing configured to be arranged at a second side of the flexible object, and a second magnetic fixing unit connected to the second housing. Wherein, the first magnetic fixing unit and the second magnetic fixing unit are configured to hold the first housing and the second housing on the flexible object by magnetic force.