Synchronised variation of source conditions of an atmospheric pressure chemical ionisation mass spectrometer coupled to a gas chromatograph to improve stability during analysis
Womble Bond Dickinson (US) LLP `Vernon Deborah M.`Misley Heath T.
摘要：
A mass spectrometer is disclosed comprising a gas chromatography separation device, an atmospheric pressure ionization ion source and a control system arranged and adapted: (i) to operate the atmospheric pressure ionization ion source at one or more first settings for a first period of time while one or more solvents elute from the gas chromatography separation device during a solvent front; and then (ii) to operate the atmospheric pressure ionization ion source at one or more second different settings for a second subsequent period of time while one or more analytes elute from the gas chromatography separation device.
