Yun-Long Li;Andrew P. Combs;Eddy W. Yue;Hui-Yin Li
发明人:
Yun-Long Li,Andrew P. Combs,Eddy W. Yue,Hui-Yin Li
申请号：
US12972155
公开号：
US08680108B2
申请日:
2010.12.17
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides fused aryl and heteroaryl derivatives of Formula I:wherein X, V, Y, U, W, Z, R1, R2, Cy, and Ar are defined herein, that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases.
