THE BRIGHAM AND WOMEN'S HOSPITAL, INC.;BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
发明人:
AGARWAL, SANDEEP K.,SCHNEIDER, DANIEL J.,BRENNER, MICHAEL B.
申请号:
CA2805267
公开号:
CA2805267C
申请日:
2011.05.04
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Methods of treating a subject having fibrosis or at risk of developing fibrosis by administering a Cadherin-11 (CDH11 ) antagonist are provided. The treatment may be administered to subjects with dermal or non-dermal fibrosis, including lung, liver or kidney fibrosis or idiopathic pulmonary fibrosis. Methods of assessing the levels of CDH11 in a subject and determining fibrosis or risk of developing fibrosis are also provided.