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SPOJ AZOLKARBOKSAMIDA ILI NJEGOVA SOL
专利权人:
ASTELLAS PHARMA INC.
发明人:
SUGASAWA, KEIZO,KAWAGUCHI, KENICHI,NOMURA, TAKAHO,MATSUMOTO, SHUNICHIRO,SHIN, TAKASHI,AZAMI, HIDENORI,ABE, TOMOAKI,SUGA, AKIRA,SEO, RYUSHI,TANAHASHI, MASAYUKI,WATANABE, TORU
申请号:
HRP20140970
公开号:
HRP20140970T1
申请日:
2014.10.10
申请国别(地区):
HR
年份:
2015
代理人:
摘要:
[Object] To provide a therapeutic and/or prophylactic agent for urinary frequency, urinary urgency, and urinary incontinence associated with various lower urinary tract diseases including overactive bladder, various lower urinary tract diseases accompanied by lower urinary tract pain, such as interstitial cystitis, chronic prostatitis, and the like, and various diseases accompanied by pain, based on an excellent trkA receptor inhibitory action. [Means for Solution] A novel azolecarboxamide compound in which a thiazole ring or an oxazole ring is bonded to a benzene ring, a pyridine ring, a pyridazine ring, a thiophene ring, a pyrazole ring or a pyrrole ring through carboxamide, or a salt thereof is confirmed to have a potent trkA receptor inhibitory activity, and found to be capable of being used as a therapeutic and/or prophylactic agent which is excellent in efficacy and safety for urinary frequency, urinary urgency, and urinary incontinence associated with various lower urinary tract diseases including overactive bladder, various lower urinary tract diseases accompanied by lower urinary tract pain, such as interstitial cystitis, chronic prostatitis, and the like, and various diseases accompanied by pain, thereby completing the present invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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