Bristol-Myers Squibb Company;Amira Pharmaceuticals, Inc.
发明人:
BRITTAIN, Jason,SEIDERS, Thomas,KING, Christopher,ROSSO, Victor
申请号:
LT11805292
公开号:
LT2648726T
申请日:
2011.12.07
申请国别(地区):
LT
年份:
2018
代理人:
摘要:
Described herein is the LPA1 antagonist 1-{4'-[3-methyl-4-((R)-1-phenyl-ethoxycarbonylamino)-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid (Compound 1), or pharmaceutically acceptable salts thereof. Also described are methods of preparing the LPA1 antagonist, or pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions suitable for administration to a mammal that include the LPA1 antagonist, or pharmaceutically acceptable salt thereof, and methods of using such pharmaceutical compositions for treating LPA-dependent or LPA-mediated diseases or conditions.