An apparatus, system and methods thereof for generating an acoustic lubrication effect along a surface of an in-dwelling medical device that is in contact with a vital tissue in a subject are provided. The vibrations comprise: Hz range cylindrical surface vibrations or kHz range surface acoustic wave (SAW) vibrations or a combination thereof. The vibrations create an acoustic lubrication effect that may reduce pain or discomfort in a subject when the apparatus is used with an indwelling medical device. The vibrations may enhance tactile sensation when the medical device is a shoe pad.
