The present invention relates to a cosmetic composition for a keratin substance, for example the skin such as that of the face, comprising: (i) at least one moisturizer; (ii) at least one film-forming polymer; and (iii) a combination of the following fillers: (a) hydrophobic silica: (b) perlite; (c) urethane polymer powder; and (d) acrylic polymer powder. “Long-lasting” effects of a cosmetic composition for a keratin substance comprising at least one moisturizer without creating any dry feeling can be achieved by using both a film-forming polymer and a combination of the following fillers: (a) hydrophobic silica: (b) perlite; (c) urethane polymer powder; and (d) acrylic polymer powder.