The present invention provides a tooth correctional system suitable for mixed dentition and a manufacturing method of the tooth correctional system, wherein the method comprises the following steps: building an original dentition digital model representing the original tooth state which includes at least one embedded tooth acquiring a corresponding eruption tooth standard model for each embedded tooth in the original tooth state to obtain a mixed dentition digital model producing a series of target dentition digital models according to the mixed dentition digital model and manufacturing a tooth correctional device according to the produced series of target dentition digital models. The tooth correctional system can be used for correction of teeth of patients of any ages, and is especially suitable for dental transitional period adolescent patients simultaneously with deciduous teeth and permanent teeth.
