ABSTRACT Title: A System and kit for Non-invasive Detection of Peptic Ulcer Disease, Non-ulcerous Dyspepsia and Helicobacter Pylori infection A system and a kit for rapid, easy and selective detection of peptic ulcer disease (PUD) (encompassing both gastric and duodenal ulcers) and non-ulcerous dyspepsia (NUD) along with Helicobacter pylori (H. pylori) infection in human stomach is provided and particularly relates to a system adapted for human breath analysis thus facilitating non-invasive and precise detection of PUD and NUD as the complicacies of H. pylori infection, following oral administration of a natural fruit juice. The system specifically evaluates the actual disease state whether it is PUD or NUD by simultaneous monitoring of molecular hydrogen (H2) and stable carbon isotopes of CO2 molecule (i.e. 12CO2 and 13CO2) in exhaled breath both in off-line and on-line mode and is completely free of administration of any isotope enriched substrates to subjects of analysis. The kit contains a citric acid containing natural fruit juice as a test meal and a suitable container for collecting the patient�s breath sample. Fig. 4