MARSHALL, Andrew James,BUCHANAN, Christina Maree,REWCASTLE, Gordon William,LU, Guo-Liang,FLANAGAN, Jack Urquhart,BONNET, Muriel,SHEPHERD, Peter Robin,JAMIESON, Stephen Michael Frazer,GAMAGE, Swarnalat
申请号：
EP17867398
公开号：
EP3535243A4
申请日:
2017.11.03
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
Disclosed are tricyclic heterocyclic compounds having kinase inhibitory activity, pharmaceutical compositions and kits comprising the compounds, and use of the compounds in the treatment of or in medicaments for the treatment of various diseases and conditions. In particular, disclosed are tricyclic heterocyclic compounds of the formula (I) having CSF-1R (c-FMS kinase) inhibitory activity and their use in the treatment of various diseases and conditions, such as those mediated by CSF-1R, including proliferative or neoplastic diseases and conditions, including cancers, and bone, inflammatory, and autoimmune diseases and conditions.
