包含免疫刺激性及抗原性多肽的酵母菌疫苗載體以及其使用方法农业专利-农业专业知识服务系统

专利权人:: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS;THE TEXAS A&M UNIVERSITY SYSTEM

发明人:: FAULKNER, OLIVIA B.,福克纳　奥莉维亚　Ｂ,福克納　奧莉維亞　Ｂ,BIELKE, LISA,贝尔琪　丽莎,貝爾琪　麗莎,CALHOUN, LEONA NICOLE,考亨　李奥娜　妮可,考亨　李奧娜　妮可,BERGHMAN, LUC,柏格曼　路克,HARGIS, BILLY,哈吉斯　比利,福克纳奥莉维亚 B,福克納奧莉維亞 B,贝尔琪丽莎,貝爾琪麗莎,考亨李奥娜妮可,考亨李奧娜妮可,柏格曼路克,哈吉斯比利

摘要：: Vaccine compositions including a yeast comprising an immunostimulatory polypeptide and optionally an antigenic polypeptide are provided herein. The immunostimulatory polypeptide and the antigenic polypeptide are expressed or displayed on the surface of the yeast vaccine composition. Methods of using the vaccine composition to vaccinate subjects are also provided.本發明提供一種疫苗組合物，其包含含有免疫刺激性多肽與任選的抗原性多肽的酵母菌。免疫刺激性多肽與抗原性多肽表達或顯示於酵母菌疫苗組合物的表面上。本發明亦提供一種使用疫苗組合物接種於受試者的方法。