DAVIDSON JAMES EDWARD PAUL,MURRAY JAMES BROOKE,FEJES IMRE,CHEN I-JEN,DURAND DIDIER,GENESTE OLIVIER,STARCK JÉRÔME-BENOÎT,LE DIGUARHER THIERRY,GUILLOUZIC ANNE-FRANÇOISE,DE NANTEUIL GUILLAUME,LE TIRAN AR
申请号：
NZ62662314
公开号：
NZ626623A
申请日:
2014.06.24
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
Disclosed herein is a pyrrole compound of formula I, wherein the variables are defined in the specification, pharmaceutical compositions containing the compound and processes for the preparation thereof. Additionally disclosed is the use of the compounds or compositions in the treatment of cancers, auto-immune disease and disease of the immune system. In one embodiment the compound is 5-(5-chloro-2-{ [(3R)-3-methyl-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl} phenyl)-N-(4-hydroxyphenyl)-1,2-dimethyl-N-(pyridin-4-yl)-1H-pyrrole-3-carboxamide.
