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DERIVATIVES OF 5- (ACILAMINE) INDAZOL AS QUINASE INHIBITORS.
- 专利权人:
- GLAXOSMITHKLINE LLC
- 发明人:
- DREWRY, DAVID,EVANS, BRIAN,GOODMAN, KRISTA,GREEN, DARREN VICTOR S.,JUNG, DAVID,LEE, DENIS,STAVENGER, ROBERT,WADMAN, SJOERD
- 申请号：
- ES04755699
- 公开号：
- ES2374272T3
- 申请日:
- 2004.06.18
- 申请国别(地区):
- ES
- 年份:
- 2012
- 代理人:
- 摘要：
- A compound selected from the group: 4- (4-fluorophenyl) -N-1H-indazol-5-yl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide； 4- [3,4-bis (ethyloxy) phenyl] -N-1H-indazol-5-yl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide； N-1H-indazol-5-yl-6-methyl-4- [4- (methylsulfonyl) phenyl] -2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide； N-1H-indazol-5-yl-6-methyl-2-oxo-4- (3-thienyl) -1,2,3,4-tetrahydro-5-pyrimidinecarboxamide； N-1H-indazol-5-yl-4,6-dimethyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide； N-1H-indazol-5-yl-6-methyl-4- (1-naphthalenyl) -2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide； N-1H-indazol-5-yl-6-methyl-4- (2-naphthalenyl) -2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide； 4- {5 - [(1H-indazol-5-ylamino) carbonyl] -6-methyl-2-oxo-1,2,3,4-tetrahydro-4-pyrimidinyl} benzoic acid； 4- (2,4-Difluorophenyl) -N-1H-indazol-5-yl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide； N-1H-indazol-5-yl-6-methyl-4- [3- (methyloxy) phenyl] -2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide； N-1H-indazol-5-yl-6-methyl-4- [2- (methyloxy) phenyl] -2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide； 4- (4-cyanophenyl) -N-1H-indazol-5-yl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide； 3- {5 - [(1H-indazol-5-ylamino) carbonyl] -6-methyl-2-oxo-1,2,3,4-tetrahydro-4-pyrimidinyl} benzoic acid； 4- (2-fluorophenyl) -N-1H-indazol-5-yl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide； 4- (3-Chloro-4-fluorophenyl) -N-1H-indazol-5-yl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide； 4- {3 - [(2-hydroxyethyl) oxy] phenyl} -N-1H-indazol-5-yl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide； 4- (4-Bromo-2-thienyl) -N-1H-indazol-5-yl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide； 4- (4-hydroxyphenyl) -N-1H-indazol-5-yl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide； 4- (4-Chloro-2-fluorophenyl) -N-1H-indazol-5-yl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide； N-1H-indazol-5-yl-6-methyl-
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
