By the invention a dental interproximal cleaning device is provided including a handle and a holder, the handle having a proximal end and a distal end, the holder having a base joined to the distal end and a bifurcation forming two branches and a cleaning element extending between the branches of the bifurcation. The cleaning element has a thread element and a brush element, the thread element having a length corresponding at least to the transversal dimension of a tooth or to the transversal dimension of a contact surface between said tooth and an adjacent tooth, and the brush element having a length at least corresponding to one half of the length of the thread element.