Jesper F. Lau,Florian Dismer,Kim Vilbour Andersen,Bhavesh Premdjee
申请号：
US16632095
公开号：
US20200165313A1
申请日:
2018.07.19
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention relates to compounds derived from the EGF(A) domain of LDL-R, in particular compounds comprising a peptide analogue of the wild-type EGF(A) (LDL-R(293-332)) sequence and at least one substituent comprising at least one fatty acid group. The invention also relates to a pharmaceutical composition thereof and use a medicament. The novel EGF(A) compounds of the invention are useful as treatment e.g. in the field of cholesterol lowering, dyslipidaemia and cardiovascular disease.
