PIREAUX, VALERIE,DEMOULIN, STEPHANIE,GODFROID, EDMOND,TASSIGNON, JOEL,DEROCHETTE, SANDRINE,GUYAUX, MICHEL
申请号：
CA3089358
公开号：
CA3089358A1
申请日:
2019.02.01
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present invention relates to a protein or polypeptide comprising an Ixodes ricinus salivary gland polypeptide, a fragment or a variant thereof, and its use for inhibiting the extrinsic coagulation pathway and for treating and/or preventing diseases and conditions associated to the recruitment and activation of neutrophils following activation of the extrinsic coagulation pathway. In particular, the present invention relates to the use of a protein comprising an Ixodes ricinus salivary gland polypeptide, a fragment or a variant thereof, for the treatment and/or prevention of any thrombotic events associated with the recruitment and activation of neutrophils following activation of the extrinsic coagulation pathway.
