Michael March Schmidt,Eric Steven Furfine,Amy Jada Andreucci,Thomas M. Barnes
申请号:
US14358857
公开号:
US20140315817A1
申请日:
2012.11.18
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention provides methods and materials for making and using variant serum albumin amino acid sequences which exhibit improved properties compared to wild type serum albumin sequences. The invention further provides methods and materials for making and using fusion proteins in which the variant serum albumin amino acid sequences are fused to a therapeutic or diagnostic agent, such as a therapeutic protein, or a functional fragment or variant thereof that maintains activity, and exhibits improved properties.