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Slow-release therapy for hypertension and renal dysfunction
专利权人:
ТЕЙДЗИН ФАРМА ЛИМИТЕД (JP)
发明人:
СИРАКУРА Такаси (JP),ТАМУРА Мидзухо (JP),ТАКАХАСИ Ёсимаса (JP),КУВАХАРА Иппэй (JP)
申请号:
RU2013103366/15
公开号:
RU2013103366A
申请日:
2011.06.24
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A sustained release pharmaceutical composition for treating or preventing hypertension or usually high blood pressure, which contains, as an active component, a 2-phenylthiazole compound represented by the following chemical formula (I): wherein R represents a alkoxy group, morpholino group, 4-methylpiperazin-1- an alkyl group or a piperidino group; R is a nitro group or a cyano group; X is a carboxyl group or a C1-6 alkoxycarbonyl group; and Y represents a hydrogen atom or a C 1-6 alkyl group, or a pharmaceutically acceptable salt thereof. The pharmaceutical composition of claim 1, wherein hypertension or usually high blood pressure means hypertension or usually high blood pressure with hyperuricemia or gout. The pharmaceutical composition according to claim 1, wherein hypertension or usually high blood pressure means hypertension or usually high blood pressure with renal dysfunction. The pharmaceutical composition according to any one of claims 1 to 3, where where the 2-phenylthiazole compound represented by formula (I) is 2- (3-cyano-4-isobutylchufenyl) -4-methyl-5-thiazolecarboxylic acid or a pharmaceutically acceptable salt thereof .5. Slow-release pharmaceutical composition for treating or preventing renal dysfunction, which contains, as an active component, a 2-phenylthiazole compound represented by formula (I) or a pharmaceutically acceptable salt thereof. 6. The pharmaceutical composition for sustained release according to claim 5, wherein renal dysfunction means renal dysfunction with hyperuricemia or gout. The pharmaceutical composition of claim 5, wherein the renal dysfunction is1. Фармацевтическая композиция с замедленным высвобождением для лечения или предупреждения гипертонии или обычно высокого артериального давления, которая содержит в качестве активного компонента соединение 2-фенилтиазола, представленное следующей химической формулой (I):гдеRозначает Cалкоксигруппу, морфолино-группу, 4-метилпиперазин-1-ильную группу или пиперидиногруппу;Rознача
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