Che-Leung Law,Julie McEarchern,Jonathan G. Drachman
申请号:
US12891716
公开号:
US08663642B2
申请日:
2010.09.27
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Disclosed are anti-CD70 antibodies and derivatives thereof conjugated to cytotoxic, immunosuppressive, or other therapeutic agents, as well as pharmaceutical compositions and kits comprising the antibody- and antibody derivative-drug conjugates. Also disclosed are methods, for the treatment of CD70-expressing cancers and immunological disorders, comprising administering to a subject the disclosed pharmaceutical compositions.