Implanting an endoluminal device in a patient includes advancing the device to a treatment location in a patient, and deploying the device such that it contacts body tissue forming an inner wall of a body lumen. The implantation further includes inciting an immune reaction in the body tissue via a sclerosant in a coating of the device, and promoting ingrowth of new body tissue triggered by the sclerosant about the device via a bioremodelable material in the coating so as to anchor the device at the treatment location.