Composition for prevention, amelioration or treatment of degenerative neurological diseases, comprising a mixed extract of mulberry coconut and bukkyou skin
The present invention relates to a composition for the prevention, amelioration or treatment of degenerative neurological diseases, which contains a mixed extract of Mulberry and Poria cocos peel as an active ingredient, and uses thereof. The mixed extract of mulberry coconut and budweed skin, which is an active ingredient contained in, has beta amyloid production and tau phosphorylation inhibition, nerve cell protection action by NGF production promotion action, nerve cell protection and memory ability improvement action by acetylcholinesterase inhibition Can be usefully used as a pharmaceutical composition for preventing or treating degenerative neurological diseases, or as a health food for the above purpose.本発明は、桑椹子(Mulberry)およびブクリョウ皮(Poria cocos peel)混合抽出物を有効成分として含有する退行性神経疾患の予防、改善または治療用組成物およびこれらの利用に関し、本発明の組成物に含まれる有効成分である桑椹子およびブクリョウ皮の混合抽出物は、ベータアミロイド生成およびタウリン酸化抑制、NGF生成促進作用による神経細胞保護作用、神経細胞保護およびアセチルコリンエステラーゼ抑制による記憶力改善作用を有することによって、退行性神経疾患の予防または治療用薬学的組成物、または前記目的の健康食品として有用に用いられ得る。