Ataxia telengiectasia and Rad3-related (ATR) protein kinase inhibitors

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专利权人:

Atrin Pharmaceuticals LLC

发明人:

Henry Joseph Breslin,Oren Gilad

申请号：

US15498631

公开号：

US09981989B2

申请日:

2017.04.27

申请国别(地区):

US

年份:

2018

代理人:

摘要：

Macrocyclic compounds having the structure of Formula (A), or pharmaceutically acceptable salts thereof, are provided,wherein R1, R2, R3, R4 and R5 are defined herein. Also provided are pharmaceutical compositions comprising the macrocyclic compound and methods for treating cancer in a patient comprising administering to the patient the macrocyclic compound.

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