NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF

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专利权人:

Sage Therapeutics, Inc.

发明人:

MARTINEZ BOTELLA, Gabriel,HARRISON, Boyd, L.,ROBICHAUD, Albert, Jean,SALITURO, Francesco, Gerald,HERR, Robert, Jason,KARGBO, Robert, Borbo

申请号：

EP20140837132

公开号：

EP3035940(B1)

申请日:

2014.08.22

申请国别(地区):

欧洲专利局

年份:

2018

代理人:

摘要：

Described herein are neuroactive steroids of the Formula (I): or a pharmaceutically acceptable salt thereof; wherein -------, R1, R2, R5, A and L are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.

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