Blythe SATHER,G. Grant WELSTEAD,David A. BUMCROT,Ari E. FRIEDLAND,Jon JONES,Morgan L. MAEDER,Chris NYE,Eugenio Marco RUBIO,Ruth SALMON
申请号:
US16098845
公开号:
US20190136230A1
申请日:
2017.05.06
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Provided are CRIS PR/CAS-related methods, compositions and components for editing a target nucleic acid sequence, or modulating expression of a target nucleic acid sequence, and applications thereof in connection with cancer immunotherapy comprising adoptive transfer of engineered T cells or T cell precursors.