Modified exendins and uses thereof

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专利权人:

Aifeng Lv

发明人:

Aifeng Lv,Changan Sun,Yali Wang

申请号：

US13334912

公开号：

US08716221B2

申请日:

2011.12.22

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The present invention discloses a modified exendin or pharmaceutically acceptable salts thereof, wherein the modified exendin comprises an amino acid sequence having at least 90% sequence identity to SEQ ID No. 17 and the amino acid sequence has a higher stability than the non-modified exendin of SEQ ID No. 4. These compounds are useful in treating type 2 diabetes as GLP-1 receptor agonists.

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中国工程科技知识中心

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http://www.ckcest.cn/home/