A baroreceptor activation device (70) is positioned near a baroreceptor, preferably a baroreceptor located in the carotid sinus. A control system (60) may be used to modulate the baroreceptor activation device (70). The control system (60) may utilize an algorithm defining a stimulus regimen which promotes long term efficacy and reduces power requirements/consumption. A mapping method permits the baroreceptor activation device (70) to be precisely located to maximize therapeutic efficacy. The baroreceptor activation device (70) may utilize electrodes to activate the baroreceptors. The electrodes may be adapted for connection to the carotid arteries at or near the carotid sinus, and may be designed to minimize extraneous tissue simulation.
